Progesterone

Progesterone in Men?

Before you think we are crazy, this hormone should be considered as a hormone with properties somewhere in the middle of testosterone and estrogen. Progesterone has its reputation as a female hormone due to its role in promoting pregnancy. But natural progesterone is still present in the male and also plays an important role in male physiology; this however has not yet been made totally clear.

Just as testosterone use affects women more noticeably than men, other hormones found in smaller amounts in men such as estrogen and progesterone can affect men more profoundly than women. We know that too much estrogen and progesterone will lead to loss of muscle mass, gains in fat and loss of libido. At the right levels, but more importantly the ratio/proper balance of these hormones could actually be beneficial for libido, prostate health, cardiovascular health and body composition.

Some interesting Research Studies

In 1988 a very important study was done at Nanjing Medical College in China where progesterone reduced the prostate weights of test animals.

Six different studies at the University of Milan in Italy, the University of Turku in Finland, Montreal General Hospital in Quebec, St. George's Hospital in London, the University of Mainz in Germany and the Roswell Park Memorial Institute in New York all independently had results that suggest that progesterone is a powerful 5-alpha reductase inhibitor that stops the conversion of testosterone into DHT in test animals.

At Staten Island College in New York and Mt. Sinai Medical School (also in New York ) progesterone was shown to raise the level of androstenedione in the prostate gland itself. Remember that a healthy prostate needs an abundance of androgens such as testosterone and androstenedione and DHEA to function well as it does in your youth.

At the University of Maryland in Baltimore human prostate cells were shown to have progesterone receptor sites. This was also demonstrated at the Institute of Clinical Medicine in Rome.

The Center for Drug Research in India did four different studies suggesting that progesterone shrank enlarged rat prostates, progesterone antagonized the stimulating effects of estrogen, that progesterone stimulates alkaline phosphatase and depressed acid phosphatase in the prostate and generally is supportive of proper prostate function.

At the University of Laval in Quebec progesterone inhibited estrogen from binding to the prostate and progesterone receptors were clearly demonstrated.
At the Institute for Biological Medical Experiments in Buenos Aires it was shown progesterone shrank prostate weight in test animals as well as reduced 5-alpha reductase activity.

At Central Hospital University in Paris progesterone was shown to inhibit the formation of DHT as well as binding of it to the prostate. DHT content in the prostate is the single most causative factor in prostate disease.

At the Biochemical Medical Laboratory in France the doctors demonstrated in human BPH tissue there are more progesterone receptors which show how responsive the prostate is to this hormone.

At the Institute of Clinical Chemistry in Bochum, Germany progesterone in human BPH tissue reduced the activity of 5-alpha reductase strongly.

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